Source National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; University of Tokyo, Tokyo, Japan. Electronic address: tsunodakoichi@kankakuki.go.jp. Undiagnosed submucous cleft palate interfering with inhalation therapy and a solution.http://www.ncbi.nlm.nih.gov/PubMed/22999274?dopt=Abstracthttp://www.allergiafarmaci.allergo.it/category/jaci/feed/Allergia a farmaci [...] leggi tutto »
Undiagnosed submucous cleft palate interfering with inhalation therapy and a solution.
Source National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; University of Tokyo, Tokyo, Japan. Electronic address: tsunodakoichi@kankakuki.go.jp. Undiagnosed submucous cleft palate interfering with inhalation therapy and a solution.http://www.ncbi.nlm.nih.gov/PubMed/22999274?dopt=Abstracthttp://www.allergiafarmaci.allergo.it/category/jaci/feed/Allergia a farmaci [...] leggi tutto »
Primary T-cell immunodeficiency with immunodysregulation caused by autosomal recessive LCK deficiency.
Abstract BACKGROUND: Signals emanating from the antigen T-cell receptor (TCR) are required for T-cell development and function. The T lymphocyte-specific protein tyrosine kinase (Lck) is a key component of the [...] leggi tutto »
Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection.
Abstract BACKGROUND: Respiratory viral infection, including respiratory syncytial virus (RSV) and rhinovirus, has been linked to respiratory disease in pediatric patients, including severe acute bronchiolitis and asthma exacerbation. OBJECTIVE: The [...] leggi tutto »
Fel d 1-derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: A randomized, placebo-controlled study.
Abstract BACKGROUND: Allergic rhinoconjunctivitis is an increasingly common source of morbidity, with sensitivity to cats accounting for 10% to 15% of disease burden. Allergy to cats is also a major [...] leggi tutto »
Spleen tyrosine kinase inhibition attenuates airway hyperresponsiveness and pollution-induced enhanced airway response in a chronic mouse model of asthma.
Abstract BACKGROUND: Asthma is a chronic inflammatory disease characterized by airways hyperresponsiveness (AHR), reversible airflow obstruction, airway remodeling, and episodic exacerbations caused by air pollutants, such as particulate matter (PM; [...] leggi tutto »
Deficient antiviral immune responses in childhood: Distinct roles of atopy and asthma.
Abstract BACKGROUND: Impaired immune response to viral infections in atopic asthmatic patients has been recently reported and debated. Whether this condition is present in childhood and whether it is affected [...] leggi tutto »
LRBA gene deletion in a patient presenting with autoimmunity without hypogammaglobulinemia.
Source Molecular Immunology Unit, Wolfson Centre for Gene Therapy of Childhood Disease, University College London (UCL) Institute of Child Health, London, United Kingdom; Great Ormond Street Hospital for Children National [...] leggi tutto »
Repeated low-dose intradermal allergen injection suppresses allergen-induced cutaneous late responses.
Abstract BACKGROUND: Subcutaneous immunotherapy with high-dose grass pollen was first described more than 100 years ago. This treatment suppresses allergen-induced cutaneous late responses, with lesser effects on early responses. In [...] leggi tutto »
Limitations of reliance on specific IgE for epidemiologic surveillance of food allergy.
Source Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Md; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md. Limitations [...] leggi tutto »